fa بررسی مروری بر اثرات درمانی روغن بذر کتان در ترمیم زخم تخصصي Special پژوهشي Research <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">زخم</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">های پوستی یکی از شایع</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">ترین آسیب</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">ها در انسان است که هزینه</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">های زیادی برای مراقبت</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">های بهداشتی و پیامدهای جسمی، روانی و اجتماعی جدی طولانی مدت یا دائمی دارد. بهبود زخم شامل فرآیندهایی مانند مهاجرت سلولی، رسوب ماتریکس خارج سلولی، بازسازی و رگ</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">زایی است. علاوه بر این، واکنش</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">های آنتی</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">اکسیدانی و ضدالتهابی نقش کلیدی در روند بهبود زخم دارند. ترمیم زخم فرآیند پیچیده</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">ای است که به عوامل و شرایط خاصی نیاز دارد و</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">کرم</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">های ضدمیکروبی تجاری و</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">عوامل پانسمان در بهبود زخم</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">های</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">سوختگی عمیق ناموفق هستند.</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">مصرف</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">داروهایی</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">که بهبود</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">زخم را تسریع می</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">کنند، به</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">ویژه داروهای</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">گیاهی</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">که</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">عمدتاً بی</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">خطر و مؤثر هستند، رایج</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">تر می</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">شوند. مطالعات نشان داده است که روغن بذر کتان&nbsp;</span></span></span><span dir="RTL" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">دارای فعالیت های&nbsp;</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">ضد التهابی، ضدمیکروبی و آنتی</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">اکسیدانی است. به</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">طور سنتی استفاده می</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">شود. نشان داده شده است که دانه کتان اثرات مثبتی بر بسیاری از انواع زخم</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">ها، مانند التیام زخم</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">ها و سوختگی</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">پوستی دارد. در&nbsp; این مقاله مروری، پایگاه‌های اطلاعاتی </span></span></span><span style="font-size:10.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times="">Google Scholar</span></span></span><span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">، </span></span></span><span style="font-size:10.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times="">Pupmed</span></span></span><span dir="RTL" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:"> و </span></span></span><span style="font-size:10.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times="">Scopus</span></span></span><span dir="RTL" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:"> با کلمات کلیدی </span></span></span><span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">روغن بذر کتان، بهبود زخم و بازسازی از سال 2014 تا 2022 جستجو شد و اثرات مثبت استفاده از دانه کتان در انواع مختلف ترمیم زخم و بهبود ضایعات پوستی در مطالعات انسانی، مدل</span></span></span> <span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="line-height:107%"><span b="" baran="" style="font-family:">های حیوانی و آزمایشگاهی بررسی گردید. </span></span></span> <div style="text-align: justify;"><span style="font-size:11.0pt"><span style="line-height:107%"><span style="font-family:&quot;Times New Roman&quot;,serif">Skin ulcers are one of the most common injuries in humans, which have high costs for health care and serious long-term or permanent physical, psychological and social consequences. Wound healing involves processes such as cell migration, extracellular matrix deposition, regeneration and angiogenesis. In addition, antioxidant and anti-inflammatory reactions play a key role in the wound healing process. Wound healing is a complex process that requires specific factors and conditions, and commercial antimicrobial creams and dressing agents are unsuccessful in healing deep burn wounds. Medicines that accelerate wound healing are becoming more common, especially herbal medicines, which are mostly safe and effective. Studies have shown that<i> Linum usitatissimum</i> flaxseed oil has anti-inflammatory, antimicrobial and antioxidant activities. It is traditionally used. Flaxseed has been shown to have positive effects on many types of wounds, such as healing skin wounds and burns. In this review article, we searched GoogleScholar, Pupmed and Scopus databases with Linum usitatissimum, flaxseed oil, wound healing and regeneration Keywords from 2014 to 2022 and positive effects of the use of flaxseeds in different types of wound healing and improvement of skin lesions are investigated in human studies, animal models and in vitro. </span></span></span></div> Linum usitatissimum, روغن بذر کتان, ترمیم زخم, بازسازی, اثرات درمانی Linum usitatissimum, Flaxseed oil, Wound healing, Regeneration, Therapeutic effects 135 146 http://journalaer.com/browse.php?a_code=A-10-2-45&slc_lang=fa&sid=1 Saeed Dadashi سعید داداشی drsdadashi80@gmail.com 10031947532846001283 10031947532846001283 Yes Fatemeh Aliasl فاطمه علی اصل 10031947532846001284 10031947532846001284 No Parvin Mansouri پروین منصوری 10031947532846001285 10031947532846001285 No Majid Asghari مجید اصغری 10031947532846001286 10031947532846001286 No